And Wakeling, J. And Bagnall, G. And Colthart, I. ACE 031 is a biologic therapeutic,based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE 031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor.
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